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                首頁 > 產品中心 > 細胞生物學 > 重組蛋白 > abs04180FGF-2/FGFb (Met1-Ser154)(10ug)

                FGF-2/FGFb (Met1-Ser154)(10ug)

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                二抗、標簽抗體、對照抗體;WB相關:ECL發光液、預染marker、預制膠;IHC相關:二抗試劑盒、組化筆;IP/CoIP試劑盒;細胞因子、信號通路調節劑;血清、BSA、蛋白酶K、CTB、TTX、CEE;凋亡試劑盒、呼吸爆發試劑盒;動植物提取物...

                • 產品型號:abs04180
                • 廠商性質:生產廠家
                • 更新時間:2025-02-07
                • 訪  問  量:1262

                詳細介紹

                品牌其他品牌貨號abs04180
                規格10ug供貨周期一周
                概述
                描述Recombinant Mouse Fibroblast growth factor 2 is produced by our E.coli expression system and the target gene encoding Met1-Ser154 is expressed.
                別名Fibroblast Growth Factor 2, FGF-2, Basic Fibroblast Growth Factor, bFGF, Heparin-Binding Growth Factor 2, HBGF-2, Fgf2, Fgf-2
                形態Lyophilized from a 0.2 μm filtered solution of 20mM PB, 400mM NaCl, pH 7.0.
                來源E.coli
                氨基酸序列MAASGITSLPALPEDGGAAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHVKLQLQA EERGVVSIKGVCANRYLAMKEDGRLLASKCVTEECFFFERLESNNYNTYRSRKYSSWYVALKRTG QYKLGSKTGPGQKAILFLPMSAKS
                內毒素水平Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
                Accession #P15655
                性能
                背景FGF basic is one of 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. The 17 kDa mouse sequence has 98% aa identity with rat, and 95% identity with human, bovine, and sheep FGF basic. Binding of FGF to heparin or cell surface HSPG is necessary for binding, dimerization and activation of tyrosine kinase FGF receptors. FGF basic binds other proteins, polysaccharides and lipids with lower affinity. Expression of FGF basic is nearly ubiquitous but disruption of the mouse FGF basic gene gives a relatively mild phenotype, suggesting compensation by other FGF family members. FGF basic modulates such normal processes as angiogenesis, wound healing and tissue repair, embryonic development and differentiation, neuronal function and neural degeneration. Transgenic overexpression of FGF basic results in excessive proliferation and angiogenesis is reminiscent of a variety of pathological conditions.
                溶解方法Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
                保存方法Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
                純度Greater than 95% as determined by reducing SDS-PAGE.

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