Rabbit anti-CD278/ICOS Recombinant Monoclonal Anti

簡要描述：Rabbit anti-CD278/ICOS Recombinant Monoclonal Antibody(R104)，儲存溶液：PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

產品型號：abs171777
廠商性質：生產廠家
更新時間：2025-02-06
訪問量：1254

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藥物陽性對照抗體磷酸化抗體二抗病毒抗體標簽抗體內參抗體其它一抗

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詳細介紹

品牌	absin	CAS	-
分子式	-	純度	-
分子量	-	貨號	abs171777
規格	100uL	供貨周期	現貨
主要用途	IHC-P: 1:500	應用領域	化工,生物產業,綜合

概述
別名	Inducible T-cell costimulator; AILIM
宿主	Rabbit
反應種屬	Human
應用	IHC-P: 1:500
性能
形式	Liquid
濃度	0.5 mg/ml
純化方法	Protein A affinity column
類型	Monoclonal Antibody
克隆號	R104
儲存/保存方法	Store at -20℃ for one year.
存儲溶液	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
靶標
背景說明	Inducible T cell costimulatory factor (ICOS, cluster of differentiation, CD278) is an activated costimulatory immune checkpoint expressed on T cells. Its ligand ICOSL was expressed in antigen-presenting cells and somatic cells (including tumor cells in the tumor microenvironment) [PMID: 28713380, PMID: 12800259]. As one of the most common targeted immune checkpoints, ICOS is considered a possible way to develop new immunotherapy [PMID: 29544515]. Some clinical studies shown that blocking ICOS alone can inhibit tumor growth and proliferation, as well as TIGIT, CTLA4, and PD-1 [PMID: 30232519, PMID: 28803728].
細胞定位	Cell Membrane, Secreted
UniProt	Q9Y6W8
實驗結果圖
	IHC shows positive staining in paraffin-embedded human thymus. Anti-CD278/ICOS antibody was used at 1/500 dilution, Secondary antibody: #abs20040. Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
	IHC shows positive staining in paraffin-embedded human tonsil. Anti-CD278/ICOS antibody was used at 1/500 dilution, Secondary antibody: #abs20040. Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
	IHC shows positive staining in paraffin-embedded human tonsil. Anti-CD278/ICOS antibody was used at 1/500 dilution, Secondary antibody: #abs20040. Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
	Negative control: IHC shows negative staining in paraffin-embedded human kidney. Anti-CD278/ICOS antibody was used at 1/500 dilution, Secondary antibody: #abs20040. Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
溫馨提示：本產品僅作科研實驗使用，不支持臨床等研究

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Rabbit anti-CD278/ICOS Recombinant Monoclonal Anti

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